Study on the changes and neural mechanisms of early tone perception in the elderly based on intonation auditory method

Research on the early tone perception changes and neural mechanism of MCI group based on intonation auditory method

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500107119

Enrollment

Unknown

Registered

2025-08-04

Start date

2024-12-27

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment

Interventions

Mild cognitive impairment group:None

healthy controls:None

Eligibility

Sex/Gender

All

Age

60 Years to 85 Years

Inclusion criteria

Inclusion criteria: ( 1 ) Age >= 60, mother tongue is Mandarin ; ( 2 ) Normal or corrected visual acuity ; ( 3 ) Pure tone test to determine normal hearing ; ( 4 ) Confirmed as right-handed according to the Edinburgh Hand Habit Questionnaire ; ( 5 ) no professional music training experience ; ( 6 ) There were no neurological diseases affecting the experiment, no brain structural abnormalities caused by brain tumors and / or trauma, and no history of ear and head surgery.

Exclusion criteria

Exclusion criteria: ( 1 ) Illiteracy ; ( 2 ) the diagnosis of AD or any other type of dementia ; ( 3 ) any neurological disease or other serious chronic diseases, such as depression or any other mental disorders ; ( 4 ) Recently taking drugs that affect cognitive function.

Design outcomes

Primary

Measure	Time frame
Functional Near-Infrared Spectroscopy, fNIRS;Electroencephalography, EEG;The Montreal Cognitive Assessment, MoCA;Digit-span-test;Pure tone audiometry;reaction time;accurate rate;	—

Countries

China

Contacts

Public ContactLiu Yao

kunming medical university

liuyao@kmmu.edu.cn+86 136 0885 6263

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026