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Clinical study on reducing atrial fibrillation recurrence after radiofrequency ablation with vitamin C

Clinical study on the clinical phenotype of atrial fibrillation and the prognosis of catheter ablation therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107114
Enrollment
Unknown
Registered
2025-08-04
Start date
2025-08-10
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

1:Vitamin C Intravenous Administration During the Perioperative Period

Sponsors

Chinese Academy of Medical Sciences Fuwai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. 18 years old<=age<=75 years; 2. Atrial fibrillation ablation surgery for the first time; 3. Atrial fibrillation ablation surgery has been completed for at least 3 months; 4. Follow-up has been completed.

Exclusion criteria

Exclusion criteria: 1. Previous atrial fibrillation catheter ablation or surgical treatment; 2. Severely enlarged left atrium (echocardiography >55mm) or left ventricular ejection fraction < 30%; 3. Estimated glomerular filtration rate < 30 mL·min?¹·1.73 m?² or history of kidney stones; 4. Known history of glucose-6-phosphate dehydrogenase deficiency or hemochromatosis; 5. Active malignancy or life expectancy < 1 year; 6. Pregnancy or lactation; 7. Participation in another interventional clinical trial; 8. There is a lack of clinical data and the inability to collect relevant medical records.

Design outcomes

Primary

MeasureTime frame
AF, atrial flutter, or atrial tachycardia >30 s on ECG or 24 hours Holters;

Secondary

MeasureTime frame
Heart failure rehospitalization;Permanent pacemaker implantation;Stroke or cerebral hemorrhage;All-cause death;

Countries

China

Contacts

Public ContactYuhe Jia

Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College

jiayuhejyh@163.com+86 137 0135 8427

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026