bronchiectasis
Conditions
Interventions
stable control group:conventional therapy
stable intervention group:conventional therapy and Staphylococcus and Neisseria Tablets, 2 times per day, 2 tablets orally each time
Acute exacerbation control group:anti-infection therapy
Acute exacerbation intervention group:anti-infection therapy and Staphylococcus and Neisseria Tablets, 3 times per day, 4 tablets orally each time
Sponsors
Suzhou Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria of the Expert Consensus on the Diagnosis and Treatment of Adult Bronchiectasis 2012; 2. Age range: 18-80 years old; 3. The acute exacerbation period is accompanied by coughing, changes in sputum volume, purulent sputum, difficulty breathing or exercise tolerance, fatigue or discomfort, and hemoptysis. Three or more of these six symptoms worsen for more than 48 hours and are considered necessary by clinical doctors.
Exclusion criteria
Exclusion criteria: 1. Accompanied with other lung diseases such as COPD, pulmonary fibrosis, and bronchial asthma; 2. Accompanied with circulatory or vascular system diseases; 3. Accompanied with infectious diseases of other parts; 4. Usage of immunosuppressants and steroid drugs within the 3 months of enrollment; 5. Pregnant or lactating women; 6. Individuals allergic to Staphylococcus and Neisseria Tablets.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical efficacy;Number of acute exacerbations; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function;Immune function;Airway microbiota; | — |
Countries
China
Contacts
Public ContactQian Jinxian
Suzhou Municipal Hospital
Outcome results
None listed