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The relationship between postoperative diaphragm dysfunction and inflammatory factors in patients undergoing extracorporeal circulation cardiac surgery

The relationship between postoperative diaphragm dysfunction and inflammatory factors in patients undergoing extracorporeal circulation cardiac surgery

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107089
Enrollment
Unknown
Registered
2025-08-04
Start date
2024-07-11
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diaphragm dysfunction

Interventions

observation group:None

Sponsors

Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Preoperative ultrasound showed that the deviation and thickening rate of the diaphragm were within the normal range: 1) DE female>9mm, male>10mm; 2. Age>18 years old; 3. Patients undergoing extracorporeal circulation cardiac surgery in our hospital.

Exclusion criteria

Exclusion criteria: 1. History of neuromuscular disorders such as myasthenia gravis, myasthenia gravis syndrome, periodic paralysis, and polymyositis; 2. Previous thoracotomy and pneumothorax; 3.BMI>35; 4. Postoperative subcutaneous emphysema significantly affects ultrasound imaging examination; 5. Patients with extensive burns and scars in the chest area or previous chest wounds, mastectomy, etc. that affect the effectiveness of diaphragmatic ultrasound examination; 6. Patients and their families refuse to sign a written informed consent form; 7. Patients who have a history of mental illness or cognitive impairment are unable to cooperate with the experimenter;

Design outcomes

Primary

MeasureTime frame
Interleukin-1 ß;Interleukin-6;interleukin 8;Tumor Necrosis Factor-a;diaphragm excursion;

Secondary

MeasureTime frame
Systemic immune-inflammation index;Systemic immune response index;Neutrophil to lymphocyte ratio;Lymphocyte to monocyte ratio;Platelet-to-lymphocyte ratio;

Countries

China

Contacts

Public ContactLi Liu

Affiliated Hospital of Southwest Medical University

niuniudoctor@hotmail.com+86 138 8273 9530

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026