Intraoperative hypoxemia
Conditions
Interventions
Validation group:None
Sponsors
The Thirteenth People’s Hospital of Chongqing
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years; 2. Gastroscopy or treatment under intravenous anesthesia; 3. Signed informed consent; 4. Be able to understand the nature and risks of participating in the trial.
Exclusion criteria
Exclusion criteria: 1. Combined with severe heart disease: previous heart failure, NYHA cardiac function class IV., severe arrhythmia, unstable angina, severe valvular heart disease, or acute myocardial infarction within the past 6 months; 2. Combined with severe respiratory diseases: extremely severe chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome, recent asthma attack, persistent cough, hypersecretion of airway mucus, or preoperative hypoxemia (SpO2 1.5); 8. Preoperative drug or alcohol abuse; 9. Previous history of gastrectomy; 10. Participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypoxemia ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of onset of hypoxemia;Duration of hypoxemia;Minimum SpO? in hypoxemia;Incidence of intraoperative hypotension (MAP < 65 mmHg);Use of airway intervention during procedure;Adjustment of oxygen concentration during endoscopy;Area under the ROC curve (AUC) of prediction model;Calibration of prediction model (Hosmer-Lemeshow test);Net benefit of model (Decision Curve Analysis);Concordance between predicted and observed risk (Nomogram);External validation performance of the model; | — |
Countries
China
Contacts
Public ContactWang Yao
The Thirteenth People’s Hospital of Chongqing
Outcome results
None listed