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Correlation study and mechanism exploration of CTBP2 affecting glycolysis in nasopharyngeal carcinoma metastasis by regulating ZEB1

Correlation study and mechanism exploration of CTBP2 affecting glycolysis in nasopharyngeal carcinoma metastasis by regulating ZEB1

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107072
Enrollment
Unknown
Registered
2025-08-04
Start date
2025-08-04
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasopharyngeal carcinoma

Interventions

Nasopharyngeal carcinoma with metastasis observation group:None

Sponsors

Shenzhen Guangming District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Diagnosed or highly suspected nasopharyngeal carcinoma patients with metastasis; they can cooperate to complete relevant examinations and tissue biopsies.

Exclusion criteria

Exclusion criteria: 1. Nasopharyngeal cancer patients without local or distant metastasis. 2. Systemic diseases (immune diseases treated with immunotherapy, severe mental and psychological disorders, severe anemia, and brain diseases such as cerebral hemorrhage and stroke detected by imaging). 3. Poor compliance and inability to cooperate with examinations and biopsies.

Design outcomes

Primary

MeasureTime frame
Expression of CTBP2 and ZEB1 in the tissue;CTBP2 regulates glycolysis and metastasis in nasopharyngeal carcinoma;—

Secondary

MeasureTime frame
CTBP2 regulates ZEB1;Correlation between ZEB1 and HK2;ZEB1 regulates glycolysis and metastasis in nasopharyngeal carcinoma;—

Countries

China

Contacts

Public ContactLin Yiling

Shenzhen Guangming District People's Hospital

yllin11@163.com+86 190 2238 9513

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026