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Effectiveness of an immersive virtual reality (VR)-based mindfulness intervention (MI) to reduce depressive symptoms in patients with autoimmune arthritis (AA): a randomized control trial (RCT)

Effectiveness of an immersive virtual reality (VR)-based mindfulness intervention (MI) to reduce depressive symptoms in patients with autoimmune arthritis (AA): a randomized control trial (RCT)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107057
Enrollment
Unknown
Registered
2025-08-01
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autoimmune arthritis

Interventions

Intervention group:The intervention group in this study will receive six sessions of immersive VR-based MIs in addition to usual care.
Control group:Participants in the control group will receive usual care without immersive VR-based MI program.

Sponsors

School of Nursing and Health Sciences, Hong Kong Metropolitan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with AA aged 18 or above will be eligible. The inclusion criteria are: 1. being able to communicate in Cantonese, 2. presenting with depressive symptoms over the past two weeks based on the established criteria (DSM V) with a Patient Health Questionniare-9 score of at least five or above, 3. being able to commit to six consecutive weekly VR-based mindfulness sessions, and 4. on a stable medication regimen.

Exclusion criteria

Exclusion criteria: 1. Severe visual or auditory deficits. 2. Severe organic disease or malignant tumour. 3. A history of motion or simulator sickness. 4. History of epilepsy. 5. A recent mental disorder in the past 12 months or current psychiatric disorder that are potentially life threatening (i.e. psychosis, suicidal ideation). 6. Meditation and yoga practice within the past 6 months or will plan to start mindfulness intervention.

Design outcomes

Primary

MeasureTime frame
Symptoms of depression;

Secondary

MeasureTime frame
Symptoms of anxiety and stress;Pain intensity;Pain self-efficacy;Mindfulness level;Patient satisfaction;

Countries

China

Contacts

Public ContactWu Chung Ming, Timothy

School of Nursing and Health Sciences, Hong Kong Metropolitan University

tcmwu@hkmu.edu.hk+852 3970 8784

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026