Chronic obstructive pulmonary disease (COPD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Confirmed diagnosis of stage II.-III. moderate-severe COPD disease, and in the stable period within 3 months before randomization; 2. Gender is not limited, between 40 and 80 years old; 3. Patients who voluntarily participate in the trial and cooperate with active and good compliance; 4. Patients who did not participate in regular activities of various exercises in the first six months of the trial (> 2 times a week, 50 min/time exercise)
Exclusion criteria
Exclusion criteria: 1. Patients under 40 years old and over 80 years old; 2. Diagnosed with COPD disease, but the patient is in the acute exacerbation stage and needs to be hospitalized or targeted drug treatment; 3. Patients with COPD combined with asthma, lung infection, tuberculosis, bronchiectasis, lung cancer and other respiratory diseases who are not suitable for rehabilitation exercise; 4. Patients with COPD combined with serious major diseases of the heart, brain, blood vessels, liver, kidney, digestion, endocrine, nerves and other systems; 5. Have mental or unconscious disorders, causing the patient to be unable to cooperate with treatment and evaluation; 6. Subjects who are participating in other clinical intervention or drug trials at the same time; 7. Patients with musculoskeletal diseases or open injuries who are not suitable for limb muscle strength assessment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ratio of forced expiratory volume in the first second (FEV1) to forced vital capacity (FVC).;The six-minute walk test;Respiratory muscle surface EMG signal ; | — |
Secondary
| Measure | Time frame |
|---|---|
| St George's Respiratory Questionnaire;Core isokinetic muscle strength test;Kinematic detection of respiratory chain; | — |
Countries
China
Contacts
The First Affiliated Hospital of Naval Medical University