retinal vein obstruction
Conditions
Interventions
observation group:Anti-VEGF intravitreal injection:After 5 loading injections, a follow-up examination should be conducted once a month. If the condition remains stable, the interval for the next inje
control group:Anti-VEGF intravitreal injection:After completing five injections, have a follow-up checkup once a month. If the visual acuity drops by more than five letters or one line, or if the CST
Sponsors
Inner Mongolia Chaoyu Eye Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with ME secondary to CRVO by OCT or FFA; 2. First treatment or no intraocular injection or retinal laser photocoagulation treatment within 3 months; 3.Age over 18 years old; 4.OCT examination results showed that the thickness of the macular fovea (CME) was > 250 µm; 5.Best corrected visual acuity between 0.05-0.5; 6.No traction in the macular area; 7.Complete follow-up data, and ; 8.Patients voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Previous eye diseases with cornea, lens, vitreous opacity and other refractive media affecting FFA, OCT and other examinations; 2.ME caused by other reasons;3. Previous internal eye surgery that seriously affects vision, such as after anti-glaucoma surgery, vitrectomy, etc;4.Previous glaucoma, retinal detachment, diabetic retinopathy and other eye diseases that seriously affect vision;5. Patients with severe. cardiovascular and cerebrovascular diseases and systemic diseases who cannot tolerate vitreous injection of conbercept;6.Patients with previous mental illness;7.CRVO secondary to neovascular glaucoma or iris neovascularization; 8.Those who are allergic to mydriatic drugs and local anesthetics; 9.Women who are preparing to give birth or are pregnant or lactating recently; 10. Patients with poor follow-up compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity (BCVA);Macular foveal thickness (CMT); | — |
Secondary
| Measure | Time frame |
|---|---|
| The mean change in macular foveal thickness (CMT) compared to the baseline value;Number of injections;Mean change in best corrected visual acuity (BCVA) compared to baseline; | — |
Countries
China
Contacts
Public ContactGuisen Zhang
Inner Mongolia Chaoyu Eye Hospital
Outcome results
None listed