None
Conditions
Interventions
Intravenous dexamethasone group:For parturient women undergoing cesarean section under spinal anesthesia, administer 8mg dexamethasone (dissolved in 4ml saline) intravenously after the baby is deliver
Epidural dexamethasone group:For parturient women undergoing cesarean section under spinal anesthesia, after the baby is delivered and the umbilical cord is clamped, administer 4ml of normal saline in
Placebo control group:For parturient women undergoing cesarean section under epidural anesthesia, after the baby is delivered and the umbilical cord is clamped, 4ml of normal saline is injected intrav
Sponsors
The First Affiliated Hospital of the University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
19 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1: Age greater than 18 years 2: ASA Classification I-II 3: 18.5kg/m^2<BMI<30kg/m^2 4: Planned epidural anesthesia for cesarean section.
Exclusion criteria
Exclusion criteria: 1: Hypertension during pregnancy 2: Gestational diabetes 3: Allergy to dexamethasone, opioids or local anesthetics 4: Long-term use of corticosteroids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of pain relief; | — |
Secondary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index (ISI) score;VAS Score;Pain Catastrophizing Scale (PCS) score;Edinburgh Postnatal Depression Scale (EPDS) score;motor block time; | — |
Countries
China
Contacts
Public ContactKang Fang
The First Affiliated Hospital of the University of Science and Technology of China
Outcome results
None listed