Congenital scoliosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patient Inclusion Criteria: 1. Age: 0-18 years old is recommended; 2. Visiting or receiving treatment in the Department of Orthopedics of Peking Union Medical College Hospital due to spinal deformity diseases; 3. No digestive system-related diseases in the past three years; 4. No history of smoking, alcoholism or metabolic disease; 5. No use of probiotics or antibiotics in the past 8 weeks; 6. Voluntarily participate and sign the informed consent form; If you are under 14 years old, informed consent from your guardian is required and the informed consent form is signed. Selection criteria for healthy volunteers 1. Age: 0-18 years old is recommended; 2. Being treated or receiving treatment for other non-spinal deformities and other genetic diseases in the Department of Orthopedics of Peking Union Medical College Hospital; 3. Relatives of the same age of the patient without hereditary diseases such as spinal deformity; 4. No digestive system-related diseases in the past three years; 5. No history of smoking, alcoholism or metabolic diseases; 6. No use of probiotics or antibiotics in the past 8 weeks; 7. Voluntarily participate and sign the informed consent form; If you are under 14 years old, informed consent from your guardian is required and the informed consent form is signed.
Exclusion criteria
Exclusion criteria: Patient Exclusion Criteria: 1. Patients who do not meet the inclusion criteria will be excluded; Healthy volunteer exclusion criteria: 1. Patients with other genetic disorders are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amplicon Sequence Variant, ASVs; | — |
Countries
China
Contacts
Peking Union Medical College Hospital