Locally Advanced Head and Neck Squamous Cell Carcinoma
Conditions
Interventions
Postoperative concurrent chemoradiotherapy group:N/A
Postoperative radiotherapy group:N/A
Postoperative observation group:N/A
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Retrospective Study: 1)Age >= 18 years; 2)Patients diagnosed and treated at Nanfang Hospital, Southern Medical University between January 2017 and June 2022, with no further clinical visits after June 2024 and lost to follow-up; 3)Newly diagnosed head and neck squamous cell carcinoma (HNSCC) confirmed by histopathology; 4)Locally advanced disease without distant metastasis; 5)Complete clinical data (including patient demographics, tumor characteristics, treatment details, and prognostic variables); 6)Availability of MRI, CT, or PET-CT images before and after radical treatment. 2.Prospective Study: 1) Voluntary provision of signed informed consent; 2) Age >= 18 years; 3) Newly diagnosed head and neck squamous cell carcinoma (HNSCC) confirmed by histopathology; 4) Locally advanced disease without distant metastasis; 5) Complete clinical data (including patient demographics, tumor characteristics, treatment details, and prognostic variables); 6) Availability of MRI, CT, or PET-CT images before and after radical treatment.
Exclusion criteria
Exclusion criteria: 1.History of or coexisting secondary malignancies. 2.Lack of definitive radical treatment. 3.Absence of baseline or follow-up imaging (MRI/CT/PET-CT). 4.Investigator-determined unsuitability for study participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year regional relapse-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| 3-year Progression free survival;3-year overall survival; | — |
Countries
China
Contacts
Public ContactBei Chen
Southern Medical University Southern Hospital
Outcome results
None listed