Cesarean section
Conditions
Interventions
Bupivacaine group:At the beginning of subarachnoid injection, prophylactic phenylephrine was injected at 0.35ug/kg/min
The ED50 of phenylephrine in the two groups was determined by up-down sequential method, that is, the infusion dose of phenylephrine in the next patient was determined according to the response of the
Ropivacaine group:At the beginning of subarachnoid injection, prophylactic phenylephrine was injected at 0.35ug/kg/min
Sponsors
Women's and Children's Hospital Affiliated to Ningbo University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: ASA2-3 healthy pregnant women with full-term singleton pregnancy (>=37 weeks gestation).
Exclusion criteria
Exclusion criteria: Patients with allergy to epinephrine, pre-existing or pregnancy-induced hypertension, cardio-cerebrovascular disease, multiple pregnancy, diabetes mellitus, weight 90kg, height 170cm, significant coexisting maternal diseases, rupture of membranes, and placenta previa, and contraindications to spinal anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ED50; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure; the time from uterine incision to fetal delivery; | — |
Countries
China
Contacts
Public ContactChen Junyan
Women's and Children's Hospital Affiliated to Ningbo University
Outcome results
None listed