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Study on the anesthetic effect of different doses of Afentanil combined with remazolam for fiberoptic bronchoscopy

Study on the anesthetic effect of different doses of Afentanil combined with remazolam for fiberoptic bronchoscopy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106998
Enrollment
Unknown
Registered
2025-08-01
Start date
2024-07-11
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchitis

Interventions

Experimental group A1:Afentanil, remazolam
Experimental group A2:Afentanil, remazolam
Experimental group A3:Afentanil, remazolam
Control group S:sufentanil, propofol

Sponsors

Qujiang District People's Hospital (Quzhou Second People's Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.ASA grade I ~ III; 2.Meet the indications in the Guidelines for the Application of Diagnostic Bendable Bronchoscopy in Adults (2019 edition); 3.Age 18-65 years old; 4.There is no contraindication to the use of afentanil and remazolam.

Exclusion criteria

Exclusion criteria: 1.Blood pressure greater than 150/90 MMHG or less than 90/60 MMHG; 2.Significant sinus bradycardia (heart rate less than 45 beats/min), sinus tachycardia (heart rate greater than 120 beats/min); 3.Frequent ventricular premature (more than 5 times/min); 4.Patients with an oxygen saturation of less than 92%.

Design outcomes

Primary

MeasureTime frame
SpO2, heart rate (HR), blood pressure (BP), respiratory rate (RR) at different moments;The number of cases of hypoxemia, hypotension, sinus tachycardia, sinus bradycardia, and apnea in each group during the operation was recorded.;The choking score of the patients was recorded during the operation;;

Secondary

MeasureTime frame
Intraoperative operation time and postoperative recovery time;Number of cases of patients experiencing chest tightness, nausea, vomiting, and dizziness after waking up;

Countries

China

Contacts

Public ContactMao Zhihao

Qujiang District People's Hospital (Quzhou Second People's Hospital)

1059557578@qq.com+86 13157035570

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026