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Effects of desflurane versus sevoflurane on quality of postoperative recovery in elderly patients: a prospective, double-blind, randomized controlled clinical trial.

Effects of desflurane versus sevoflurane on quality of postoperative recovery in elderly patients: a prospective, double-blind, randomized controlled clinical trial.

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106982
Enrollment
Unknown
Registered
2025-08-01
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Recovery

Interventions

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 95 Years

Inclusion criteria

Inclusion criteria: 1. Age >=65 years, gender not limited; 2. Elective non-cardiac, non-neurosurgical elective surgery, estimated operation time >= 2 hours; 3. Signed the informed consent form; 4. Patients with ASA I to III.

Exclusion criteria

Exclusion criteria: 1. History of mental illness such as schizophrenia; 2. Inability to communicate due to coma, severe dementia, speech disorder, or serious illness; 3. American Society of Anesthesiologists (ASA) Class III; 4. Family history of malignant hyperthermia; 5. Participation in other clinical trials within 3 months prior to enrollment.

Design outcomes

Primary

MeasureTime frame
QoR15 score on the first postoperative day;

Secondary

MeasureTime frame
QoR15 score at postoperative day 2, day 7 and month 1;Postoperative PACU recovery time;Time to open eyes, response to commands and extubation;Time of first ambulation and postoperative exhaust;Postoperative hospital stay and total hospital stay;Inhaled anesthesia costs;Mean arterial pressure and heart rate changes;Changes of liver and kidney function and inflammation before and after operation;

Countries

China

Contacts

Public ContactJing Yang

West China Hospital, Sichuan University

yangjing@wchscu.cn+86 180 8090 2269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026