Acute cerebral infarction patients receiving mechanical ventilation
Conditions
Interventions
Control group:sham stimulation
Intervention group:?Transcutaneous Electrical Phrenic Nerve Stimulation
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old; 2.No gender restrictions; 3.Patient diagnosed with acute cerebral infarction (within 30 days of onset) through cranial CT or MRI; 4.Duration of mechanical ventilation >= 24 hours; 5.The patient or their legal guardian agrees to participate in the study and signs an informed consent form;
Exclusion criteria
Exclusion criteria: 1.There are other significant conditions that affect diaphragm function, such as severe malnutrition, irreversible respiratory pump failure caused by medullary or cervical cord injury, and irreversible damage to the phrenic nerve; 2.Significant agitation cannot be combined with ?transcutaneous electrical phrenic nerve stimulation; 3.Severe skin damage or infection at the electrode placement site; 4.Previous presence of severe lung disease (such as severe COPD, interstitial lung disease, pulmonary embolism, etc.), severe heart failure (NYHA Class IV); 5.Sepsis or shock requiring high-dose vasopressors; 6.The terminal state of the disease or expected survival period does not exceed 7 days; 7.Pacemaker implantation; 8.Pregnant or lactating women; 9.Patients whose family members express their willingness to withdraw for treatment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mecanical ventilation duration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Successful weaning rate;mRS at 90 day; | — |
Countries
China
Contacts
Public ContactLinlin Fan
Xuanwu Hospital Capital Medical University
Outcome results
None listed