Critical disease
Conditions
Interventions
Continuous/sequential feeding group:None
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.ICU length of stay after enrollment is expected to be >=5 days. 2.Patients who require enteral nutrition via a nasogastric tube. 3.Age >=18 years, no gender restrictions. 4.Indications for enteral nutrition, with a nutrition risk screening score of 3-7 points. 5.Patients who voluntarily agree or whose family members consent to participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with primary gastrointestinal diseases, such as gastrointestinal ulcers, atrophic gastritis, gastric cancer, etc. 2.Patients who have undergone gastrointestinal surgery. 3.Patients with malignant tumors, end-stage conditions, severe traumatic brain injury, extremely poor prognosis, or those who are likely to die in the short term. 4.Pregnant or breastfeeding women. 5.Patients or their family members who refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal microbiota diversity indicators at each time point; | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of different flora abundance at each time point; | — |
Countries
China
Contacts
Public ContactBo Yao
Qilu Hospital of Shandong University
Outcome results
None listed