osteoporotic vertebral compression fractures
Conditions
Interventions
DR group:Dexmedetomidine combined with ropivacaine paravertebral nerve block
CR group:Dexmedetomidine intravenous infusion combined with ropivacaine paravertebral nerve block
R group:Ropivacaine paravertebral nerve block
Sponsors
Hefei First People's Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients with OVCF are scheduled to undergo PKP surgery; 2. American Society of Anesthesiologists (ASA) Physical Condition Grade I-III; 3. Age: 50-90 years old, no gender restrictions; 4. Written informed consent was obtained;
Exclusion criteria
Exclusion criteria: 1. The patient refuses; 2. Body mass index (BMI>30 kg/m ² or 180 mmHg); 4. Puncture site infection, coagulopathy (INR>1.5, PLT<80×10?/L); 5. Allergy to related narcotic drugs; 6. Have mental or neurological disorders or language disorders that are unable to communicate and cooperate with treatment; 7. Neurologic damage or disease has been identified at the treatment site; 8. Sick sinus syndrome, atrioventricular block above degree ?; 9. Severe liver and kidney dysfunction; 10. Long-term use of sedative and analgesic drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate;Postoperative resting and exercise Visual Analogue Scale;Visual Analogue Scale;Anesthetic effect grading;Mean arterial pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay Sedation Score;The onset time of anesthesia, operation time, and duration of anesthesia;Adverse reactions(Hypotension, bradycardia, nausea and vomiting, etc);Quality of Recovery Scale-15;Age, gender, body mass index, ASA classification, education level, comorbidities, surgical segment, surgical puncture site; | — |
Countries
China
Contacts
Public ContactShen Wenli
Hefei First People's Hospital
Outcome results
None listed