Skip to content

Comparison of Efficacy and Safety Between Two Administration Modes of Tegileridine for Postoperative Pain Management: A Randomized Controlled Study

Comparison of Efficacy and Safety Between Two Administration Modes of Tegileridine for Postoperative Pain Management: A Randomized Controlled Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106920
Enrollment
Unknown
Registered
2025-07-31
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain following laparoscopic gastrectomy

Interventions

PCA Continuous Infusion Group:Tileridine PCA Continuous Infusion
Q8h Intermittent Intravenous Injection Group:Q8h Intermittent Intravenous Injection of Tileridine

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 45 to 70 years ; 2. Patients scheduled for laparoscopic gastrectomy under general anesthesia. 3. Patients undergoing endotracheal intubation under general anesthesia, with an ASA (American Society of Anesthesiologists) physical status classification of I to III. 4. Body Mass Index (BMI) between 18 kg/m^2 and 30 kg/m^2. 5. Participants fully understand the purpose, content, procedures, and risks of the trial, and voluntarily participate in the clinical trial by signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiovascular, cerebrovascular, hepatic, or renal diseases. 2. Patients with a history of mental disorders and long-term use of psychotropic medications, who have cognitive impairments. 3. Patients who are allergic to opioids or their components, or have contraindications to their use. 4. Participants who have taken part in a drug clinical trial within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Area under the curve of pain score;

Secondary

MeasureTime frame
Incidence of adverse reactions;Sedation level;Quality of recovery score at 48 hours postoperatively;Number of rescue doses;Time to first flatus after surgery;Patient satisfaction score for analgesia;

Countries

China

Contacts

Public ContactJun Hu

Weifang People's Hospital

guyueyinghui@qq.com+86 183 6567 9587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026