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Study on the relationship between fundus microcirculation and leukoencephalopathy, related affective and cognitive disorders

Study on the relationship between fundus microcirculation and leukoencephalopathy, related affective and cognitive disorders

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106917
Enrollment
Unknown
Registered
2025-07-31
Start date
2023-06-30
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic white matter lesions

Interventions

mild WMHs group:None
moderate/severe WMHs groups:None

Sponsors

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.completion of a head MRI examination consistent with the diagnosis of "cerebral white matter hyperplasia" according to the "Chinese Expert Consensus on Cerebral Small Vessel Disease;

Exclusion criteria

Exclusion criteria: 1.presence of glaucoma, retinal perforation or detachment, or optic edema; 2.inability to cooperate in completing cognitive and emotional scale assessments; 3.severe liver and kidney diseases, tumor diseases, infectious diseases, or autoimmune disorders; 4.neurological diseases such as Parkinson’s disease, multiple sclerosis, or peripheral neuropathy;

Design outcomes

Primary

MeasureTime frame
Fundus blood vessels;—

Countries

China

Contacts

Public ContactLili Zeng

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

zll11131@rjh.com.cn+86 138 1629 0607

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026