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Changes in serum choline acetyltransferase and cholinesterase levels in sepsis patients and their correlation with prognosis: a prospective, observational, single center study

Changes in serum choline acetyltransferase and cholinesterase levels in sepsis patients and their correlation with prognosis: a prospective, observational, single center study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106909
Enrollment
Unknown
Registered
2025-07-31
Start date
2024-11-26
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Sepsis group :NA
Control :NA

Sponsors

The Fourth Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years old; 2.The experimental group all met the diagnostic criteria of septsis-3; 3.Expected to be hospitalized in the ICU for at least 24 hours; 4.Voluntarily sign the informed consent form and participate in the research.

Exclusion criteria

Exclusion criteria: 1.Having a history of neurological and psychiatric disorders such as schizophrenia and Alzheimer's disease, or taking medication to alter one's mental state; 2.Patients who have undergone splenectomy in the past; 3.<2 consecutive measurements of acetylcholinesterase and acetylcholinesterase activity.

Design outcomes

Primary

MeasureTime frame
Acetyltransferase;Cholinesterase ;—

Countries

China

Contacts

Public ContactLiu Lixia

The Fourth Hospital of Hebei Medical University

47300535@hebmu.edu.cn+86 138 3318 6570

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026