Infertility
Conditions
Interventions
Test Group 1:Ultra-fast vitrification freezing + ultra-fast glass defrosting
Control group:Vitrification Media Kit,Warming Media Kit
Test Group2:Vitrification Media Kit,Warming Media Kit
Sponsors
The first people's Hospital of Yunnan Province
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Female study participants are 20 years old=2 according to the Gardner blastocyst grading criteria (assessed on the day of enrollment); 3. Indications for in vitro fertilization-embryo transfer (IVF-ET) or intracytoplasmic sperm microinjection technology (ICSI); 4. Endometrial preparation plan uses hormone replacement therapy (HRT) cycle; 5. Blastocysts need to be thawed and transferred; 6. Both husband and wife have normal chromosomes, and use autologous germ cells for assisted reproduction.
Exclusion criteria
Exclusion criteria: 1. History of 2 or more adverse pregnancy attempts; 2. Severe adenomyosis, endometriosis stage III or VI; 3. Hydrosalpinx effusion; 4. There are uterine abnormalities that affect pregnancy outcomes, such as malformed uterus (unicornuate uterus, mediastinal uterus, bicornuate uterus, double uterus), endometrial polyps, type 0~II uterine fibroids or larger uterine fibroids (=4cm), uterine adhesions, endometrial thickness <8cm on HCG day or transplantation day; 5. Systemic diseases such as reproductive tuberculosis, uncontrolled thyroid dysfunction, diabetes, hypertension, etc.; 6. Those who are not suitable for inclusion according to the investigator's judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blastocyst survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate;ß-HCG positive rate;Implantation rate;Operational efficiency (operation time for vitrification and warming); | — |
Countries
China
Contacts
Public ContactYonggang Li
The first people's Hospital of Yunnan Province
Outcome results
None listed