Mild Cognitive Impairment
Conditions
Interventions
tDCS-only group (Group A): tDCS-only group (Group A):tDCS was administered by a professionally trained therapist.
1. Standardized tDCS Stimulation Protocol:
(1) Current Parameters:
1) Stimulation in
weekly remote calibration (electrode impedance =4), seizure, or severe skin reaction
emergency response cards were provided with each device.
Sham tDCS combined with CDT group (Group B):Sham-tDCS combined with CDT (Group B): Sham-tDCS combined with CDT was administered by a professionally trained therapist.
1. Standardized tDCS Stimulation
Sponsors
The Seventh Affiliated Hospital (Shenzhen), Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. MCI patients who meet the diagnostic criteria of the 2010 Chinese Guidelines for the Diagnosis and Treatment of Dementia and Cognitive Impairment; 2. Age 60-80 years old; 3. Voluntarily accept interviews and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Have other medical diseases that are advanced, severe, or unstable, 2. Patients with neurological diseases that affect brain dysfunction or impairment in the evaluation of cognitive function, and the medication/intervention regimen is unstable (drugs that have been used stably for >= 3 months can be included as appropriate, and specific drugs and dosages need to be recorded), 3. Have a history and symptoms of traumatic brain injury, or a history of taking other special drugs that may affect cognitive function (such as cholinesterase inhibitors, benzodiazepines, antipsychotics or antiepileptic drugs), or receive other cognitive interventions (such as acupuncture, repetitive transcranial magnetic stimulation, etc.); 4. Seriously ill and unable to be interviewed; 5. History of acute cerebrovascular disease within 3 months; 6. Diagnosed dementia; 7. Patients with epilepsy; 8. Brain tumor, meningitis, cerebrovascular accident in the acute stage; 9. Those with intracranial implants; 10. Patients with recent craniocerebral injury or maxillofacial trauma are prohibited, especially with additional anterior injuries; 11. Those with implantable pacemakers or defibrillators are prohibited; 12. Pregnant women are prohibited; 13. Those who have metal implants in their bodies; Metal materials (including magnetic resonance compatible materials such as titanium), arterial clips, etc.; 14. Visual and hearing impairment cannot cooperate with the completion of the intervention program. 15.The researchers consider any condition that may harm the participant or prevent them from meeting or fulfilling the study requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal cognitive ;Non-cognitive function emotions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Working memory;Attention;Executive function;Neuropsychiatric Symptoms ;Anxiety;Depression;Sleep;Activity of daily living;Frail;Death anxiety;Heart rate variability;Electroencephalogram frequency;Blood oxygenation level dependent;Adherence; | — |
Countries
China
Contacts
Public ContactGuo Haiyan
The Seventh Affiliated Hospital (Shenzhen), Sun Yat-sen University
Outcome results
None listed