Skip to content

Study on the effect of transcutaneous auricular vagus nerve stimulation on perioperative anxiety in patients undergoing radical mastectomy for breast cancer

Study on the effect of transcutaneous auricular vagus nerve stimulation on perioperative anxiety in patients undergoing radical mastectomy for breast cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106867
Enrollment
Unknown
Registered
2025-07-31
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety of patients undergoing radical mastectomy during the perioperative period

Interventions

Sponsors

The First Hospital Of Jiaxing
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Female patients aged 20-85 years; 2. Patients who undergo elective radical breast cancer surgery; 3. Patients with preoperative anxiety with a score of 7 on the Hamilton Anxiety Scale= 4. Have primary school education or above, normal communication, listening and comprehension skills; 5. Subjects voluntarily sign the informed consent form; 6. American Medical Association ASA grade I-III;

Exclusion criteria

Exclusion criteria: 1. History of neurological or psychiatric diseases; 2. Severe cardiovascular or cerebrovascular disease; 3. Contraindications to taVNS use: recent ear trauma, ear skin damage, redness, swelling, infection, implantable electrophysiological devices, heart stents, artificial joints, etc. 4. Long-term use of psychotropic drugs (such as cortisol, antidepressants or anxiolytics);

Design outcomes

Primary

MeasureTime frame
Perioperative anxiety relief rate;

Secondary

MeasureTime frame
heart rate variability;pain score;HAMA;The incidence of postoperative delirium;Sleep quality score;Weakenedness score;

Countries

China

Contacts

Public ContactJiayi Tang

The First Hospital Of Jiaxing

tangible2020@163.com+86 182 5835 9815

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026