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EEG-Guided Anesthesia on Postoperative Delirium in Older Adults with Preoperative Cognitive Impairment: A Multicenter, Randomized, Single-Blind Clinical Trial

Effect of Intraoperative EEG-Guided Anesthesia on Postoperative Delirium in Older Adults with Preoperative Cognitive Impairment: A Multicenter, Randomized, Single-Blind Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106865
Enrollment
Unknown
Registered
2025-07-31
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Test group:Intraoperative EEG monitoring to guide anesthesia
Control group:ntraoperative EEG monitoring is not visible
anesthesia management is guided by the patients vital signs and the minimum alveolar concentration (MAC) of inhaled anesthetics

Sponsors

University Town Hospital Affiliated to Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 60 years; 2. ASA physical status > II; 3. MMSE score 2 hours; 6. Voluntarily consents to participate and signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Presence of delirium prior to surgery; 2. History of substance abuse or dependence on sedative-analgesic medications; 3. Severe communication impairments due to deafness, blindness, aphasia, etc.; 4. Surgeries for which EEG monitoring is not feasible, including brain surgery and maxillofacial surgery.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium incidence rate 1-5 days;

Secondary

MeasureTime frame
Incidence of delirium during the awakening period;Incidence of complications 30 days after surgery;All-Cause Mortality;

Countries

China

Contacts

Public ContactYanqing Zhang

University Town Hospital Affiliated to Chongqing Medical University

800466@hospital.cqmu.edu.cn+86 139 3519 5692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026