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Protective Effect of Respiratory Vaccines in Adult Chronic Disease Population: A Multicenter Study Based on Test-negative Case-control

Protective Effect of Respiratory Vaccines in Adult Chronic Disease Population: A Multicenter Study Based on Test-negative Case-control

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106855
Enrollment
Unknown
Registered
2025-07-31
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory tract infection

Interventions

Control group (negative):NA
Case group (positive):NA

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Comply with the research procedures: The subjects promise to comply with the research procedures and cooperate with the implementation of the whole - process research, including attending research - related examinations and follow - ups on time. 1. Relevant symptoms: Acute onset, meeting the indications for respiratory pathogen detection (such as presenting with influenza-like illness (ILI) or severe acute respiratory infection (SARI)); or meeting the diagnostic criteria for respiratory tract infection. 2. Disease diagnosis: The subjects meet the diagnostic criteria for respiratory tract infection. 3. Detection and time requirements: The subjects underwent laboratory pathogen testing after visiting the doctor. 4. Vaccination information: It should be possible to accurately obtain the vaccination status of respiratory pathogens of the subjects, including vaccination time, vaccine type, etc. 5. Gender and age: The subjects are adults aged 18 years or older. 6. Place of residence: The subjects are national residents.

Exclusion criteria

Exclusion criteria: 1.<18 years old; 2.Key information is missing; 3.Cases or controls without laboratory confirmation;

Design outcomes

Primary

MeasureTime frame
Vaccine protection effect;

Countries

China

Contacts

Public ContactYang Jin

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

whuhjy@sina.com+86 29 85755457

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026