Congenital Anomalies of the Kidney and Urinary tract
Conditions
Interventions
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 90 Years
Inclusion criteria
Inclusion criteria: (1) Age 0-90 years; (2) Imaging-confirmed diagnosis of congenital anomalies of the kidney and urinary tract (CAKUT), including: • Renal developmental anomalies: agenesis, hypoplasia, dysplasia, ectopic kidney, etc.; • Obstructive uropathies: ureteropelvic junction obstruction (UPJO), vesicoureteral reflux (VUR), posterior urethral valves (PUV), etc.; • Collecting-system anomalies: duplicated renal pelvis and ureter, megaureter, ureterocele, etc.; (3) Written informed consent obtained from the patient or legal guardian agreeing to participate in clinical follow-up and biospecimen collection; (4) Ability to provide complete clinical history, demographic data, imaging datasets, and to undergo regular follow-up.
Exclusion criteria
Exclusion criteria: (1) Non-congenital conditions: acquired renal or urinary tract disorders (e.g., calculi, neoplasms, post-traumatic deformities) or urinary abnormalities secondary to infection, drugs, or metabolic disease; (2) Inability to comply with follow-up or refusal to provide required clinical information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subtype classification;Radiological parameters;Renal function;Perioperative parameters (Surgical approach selection, Intraoperative data,Anatomic site of defect, Postoperative extubation time, Postoperative complications and their details, etc.);Outcome measures (categorized as functional recovery, intervention failure, or post-intervention recurrence);Pathological specimen indicators (histopathological subtype and tissue composition of the excised specimens); | — |
Countries
China
Contacts
Public ContactXuesong Li
Peking University First Hospital
Outcome results
None listed