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The influence of aerobic exercise on cardiovascular structure and function, inflammation and oxidative stress in people with impaired glucose tolerance

The protective benefits of aerobic exercise on the cardiovascular structure and function of people with impaired glucose tolerance

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106827
Enrollment
Unknown
Registered
2025-07-30
Start date
2025-08-31
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IGT

Interventions

aerobic exercise group:aerobic exercise
Control group:None

Sponsors

Fujian Normal University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) met criteria for impaired glucose tolerance; (2) self-reported lack of regular exercise habits; (3) had the awareness and ability to voluntarily participate in an exercise intervention; and (4) signed an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Diagnosed with severe heart disease, pulmonary dysfunction, and other conditions that make them unfit for exercise; (2) Cognitive and cognitive impairment; (3) Regular exercisers; and (4) Diagnosed with type 2 diabetes.

Design outcomes

Primary

MeasureTime frame
Flow-mediated dilation;—

Secondary

MeasureTime frame
Pulse wave;TNF-a;IL-6;hs-CRP;SOD;MDA;ROS;Nrf2;NLRP3;Body composition;Waist-to-Hip Ratio;Skinfold thickness;Fat thickness;BMI;IL-10;fasting plasma glucose;2 hour postprandial blood glucose;insulin;Blood lipids;HbA1c;IL-1ß;—

Countries

China

Contacts

Public ContactDan Wang

Fujian Normal University

wrofkdgock115@163.com+86 158 4003 4556

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026