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The effects of oxycodone and sufentanil postoperative analgesia on postoperative delirium after thoracoscopic lobectomy: a prospective, randomized controlled study

The effects of oxycodone and sufentanil postoperative analgesia on postoperative delirium after thoracoscopic lobectomy: a prospective, randomized controlled study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106826
Enrollment
Unknown
Registered
2025-07-30
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium (POD)

Interventions

Oxycodone group:The erector spinae plane block (ESPB) was performed on the surgical side with 20 ml of 0.33% ropivacaine after anesthesia induction and before surgery commencement. Intravenous oxycodo
Sufentanil Group:After anesthesia induction but before surgical incision, an erector spinae plane block was performed on the operative side using 20 mL of 0.33% ropivacaine. Five minutes prior to skin

Sponsors

Jianyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years 2. Adult patients scheduled for elective thoracoscopic lobectomy under general anesthesia 3. ASA physical status classification I-III 4. BMI 18.5-29.9 kg/m² 5. Written informed consent obtained

Exclusion criteria

Exclusion criteria: 1. History of psychiatric or neurological disorders; 2. Preoperative diagnosis of delirium or MMSE score <=15; 3. Inability to cooperate with study assessment scales; 4. Coagulation disorders; 5. Allergy to medications used in this study; 6. Intraoperative emergencies requiring resuscitation and/or postoperative ICU admission; 7. Surgical procedure modified from original plan; 8. Participation in other clinical trials within 30 days.

Design outcomes

Primary

MeasureTime frame
Incidence of POD within 3 days after surgery;

Secondary

MeasureTime frame
Patient's pain control status;Sedation Score;Adverse Reaction Rate;Postoperative Length of Stay;

Countries

China

Contacts

Public ContactHua Zhang

Jianyang People's Hospital

137263633@qq.com+86 152 8222 0830

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026