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Clinical Study on the Use of a New Long-Acting Local Anesthetic in Suppressing Rebound Pain After Peripheral Nerve Block

Clinical Study on the Use of a New Long-Acting Local Anesthetic in Suppressing Rebound Pain After Peripheral Nerve Block

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106818
Enrollment
Unknown
Registered
2025-07-30
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rotator Cuff Injury

Interventions

Low-dose Bupivacaine Liposome Group (Group LB1):None
High-dose Bupivacaine Liposome Group (Group LB2):None
Ropivacaine Group (Group R):None

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Aged 18 - 65 years old; 2. Body mass index BMI 18~30 kg/m^2; 3.American Society of Anesthesiologists (ASA) physical status classification I or II; 4.No history of allergy to local anesthetics; 5.No severe hepatic or renal dysfunction; 6.Ethical approval obtained, and patient has voluntarily signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Coagulation dysfunction; 2. Preoperative central or peripheral neuropathy, history of local anesthetic or opioid allergy; 3. Infection or skin damage at the puncture site; 4. Unable to cooperate and accurately describe pain NRS scorers.

Design outcomes

Primary

MeasureTime frame
The incidence of PNB-RB;

Secondary

MeasureTime frame
Resting NRS score;Time to first analgesic rescue;Movement NRS score;

Countries

China

Contacts

Public ContactNie Bingqing

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

360158103@qq.com+86 13971267447

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026