Hypotension after spinal anesthesia in cesarean section patients Perinatal hypoxia in neonates
Conditions
Interventions
Lactated Ringer's Injection Group:Titration of lactated Ringer's solution injection
Sodium Bicarbonate Ringer's Injection Group:Titration of sodium bicarbonate Ringer's solution injection
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.ASA classification levels 1-2; 2.A singleton, full-term pregnant woman; 3.Height 150~175cm, weight 50~100kg, BMI 20 kg/m2-40 kg/m^2; 4.Age range: 20 - 40;
Exclusion criteria
Exclusion criteria: 1.Include cardiovascular and cerebrovascular diseases, respiratory diseases, hematological diseases, endocrine diseases, liver and kidney system diseases, etc. 2.Multiple pregnancies; 3.Premature birth (gestational age 42 weeks); 4.Due to the patient's own condition, general anesthesia is required; 5.uring the operation, due to invasive placenta, penetrating placenta, implantation placenta and other factors, excessive bleeding may occur, intraoperative blood loss > 500 mL, Hb 90 minutes; 7.Congenital malformations; 8.Intra-spinal anesthesia contraindications, anesthesia plane exceeds T4 or is lower than T6; 9.Other adverse events during the operation; 10. Parturients who have started trial labor and have intrauterine distress and severe intraoperative blood pressure fluctuations 11. Intraoperative phenylephrine dosage >0.5mg
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lactate levels of parturients before and after entering and leaving the delivery room;Lactic acid level in umbilical cord blood; | — |
Countries
China
Contacts
Public ContactQU Liangchao
The first affiliated hostipal of nanchang university
Outcome results
None listed