Stroke
Conditions
Interventions
Experimental group:The intervention lasts for 10 days and subjects undergo routine rehabilitation training for BCI. BCI training is based on motor imagery triggered EEG-controlled electrical stimulati
Routine rehabilitation is once a day, including comprehensive hemiplegic limb training, joint mobilization, occupational therapy, hand function training, etc., with each treatment lasting about 30 min
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. First-episode stroke or a history of previous cerebral infarction with a modified Rankin Scale (mRS) score of 0 before the current onset; 2. Aged 40–85 years; 3. Diagnosed with stable ischemic stroke and a Glasgow Coma Scale (GCS) score of 15; 4. Disease duration within 7 days after stroke onset; 5. Presence of upper limb dysfunction with upper limb muscle strength graded 1–4; 6. National Institutes of Health Stroke Scale (NIHSS) score of 2–20 and no prior formal rehabilitation treatment; 7. Mini-Mental State Examination (MMSE) score >= 23; 8. Strong demand for rehabilitation and good family support; 9. Patients voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Large-area cerebral infarction, hemorrhagic infarction, or unstable vital signs; 2. Severe primary diseases of the heart, brain, lungs, liver, kidneys, etc., or malignant tumors; 3. Complications of active epilepsy, limb tremors, or inability to maintain a sitting posture; 4. Upper limb venous thrombosis in hemiplegic patients that makes rehabilitation therapy inappropriate; 5. Severe speech, attention, visual or auditory impairments; 6. Mental or cognitive dysfunction that prevents cooperation with examinations and rehabilitation treatments; 7. Contraindications to functional magnetic resonance imaging, such as having a cardiac pacemaker, metal stents, steel plates, or other metallic foreign bodies implanted in the body; 8. Contraindications to electroencephalogram examination, such as skull defects or artificial metal skulls; 9. Alcoholism or drug addiction; 10. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FMA-upper; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wolf motor function;Manual Muscle (MMT);Modified Ashworth Scale (MAS) Score;mRS Score; | — |
Countries
Chnia
Contacts
Public ContactJing Ding
Zhongshan Hospital, Fudan University
Outcome results
None listed