Effects of dexmedetomidine nasal spray combined with esketamine nasal drops on sedation and postoperative delirium in children with burn scar treated by laser

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500106780

Enrollment

Unknown

Registered

2025-07-30

Start date

2025-08-05

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Separation anxiety

Interventions

Test group:Dexmedetomidine nasal spray + Intranasal esketamine spray

Control group:Intranasal esketamine spray

Eligibility

Sex/Gender

All

Age

2 Years to 6 Years

Inclusion criteria

Inclusion criteria: For patients aged 2-6 years, ASA1-2 grade, 10.7<= weight <=28.0kg, who have hyperplastic scars caused by burns due to elective painless ultra-pulse carbon dioxide dot matrix laser, the family of each child signed the informed consent.

Exclusion criteria

Exclusion criteria: Congenital heart disease, lung disease (lung infection, bronchial asthma, etc.), known rhinitis or nasal malformations, known difficult airways.

Design outcomes

Secondary

Measure	Time frame
Vital signs at different time points;Total intraoperative dosage of propofol;	—

Primary

Measure	Time frame
Ramsay rating;Parental Anxiety Scores (PSAS) of children separated from their parents;Mask Acceptance Score (MAS);Childhood Awakening Delirium Scale (PAEDS);	—

Countries

China

Contacts

Public ContactGuangjun Hu

Wuhan Third Hospital

jeanhu@163.com+86 189 0713 2861

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026