Postoperative delirium in the elderly
Conditions
Interventions
Test group:Dexmedetomidine nasal spray nasal spray
Control group :There was no blank control for dexmedetomidine nasal spray
Sponsors
Affiliated Cancer Hospital and Institute of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) The age of the patient is 65-85 years old; (2) Patients undergoing radical surgery for gastrointestinal cancer under tracheal intubation and general anesthesia; (3) American Society of Anesthesiologists (ASA) physical status I~III; (4) Education level: primary school or above; (5) Able to communicate normally; (6) The patient voluntarily participates and signs the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Participate in other clinical trials in the past 3 months; (2) People who are allergic to dexmedetomidine; (3) The patient has severe rhinitis, deformity or nasal surgery in the past; (4) For those with education level below primary school, the cognitive function score of the Preoperative Mini-Mental State Examination (MMSE) was 180/110mmHg and<90/60mmHg).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety scores;Incidence of sleep disturbances;C-reactive protein;Quality of perioperative recovery;Postoperative pain score;Cognitive function score; | — |
Countries
China
Contacts
Public ContactWu Wenfeng
Affiliated Cancer Hospital and Institute of Guangzhou Medical University
Outcome results
None listed