persistent postural-perceptual dizziness
Conditions
Interventions
Treatment group:Transcranial alternating current stimulation
Sponsors
Shaanxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: The clinical diagnosis of PPPD must meet all five diagnostic criteria: (1). One or more symptoms of dizziness, instability and non-rotational vertigo existed in most of the time, and the duration was >= 3 months; 1). Symptoms last for A long time, often lasting for several hours, but the severity of symptoms can fluctuate; 2). Symptoms do not need to persist throughout the day. (2). There was no clear inducement for the occurrence of persistent vestibular symptoms, but the following three factors could aggravate the symptoms. 1). Upright posture; 2). Active or passive motion, but independent of direction or position of motion; 3). Exposure to moving visual stimuli or complex visual environments; (3). It is usually triggered by diseases causing dizziness/vertigo and balance disorders, including acute/paroxysmal/chronic vestibular syndrome, other neurological and medical diseases and mental and psychological diseases. 1). When the triggering event is acute/episodic disease, the patient's clinical signs and symptoms after the triggering event has resolved shows the pattern shown in the diagnostic criteria; 2). At first, the patient's symptoms may be intermittent, and then gradually evolve into persistent. B. When the trigger event is a chronic syndrome, the patient's clinical signs and symptoms is characterized by a slow onset and progressive exacerbation. (4) Symptoms bring severe pain or dysfunction to patients;(5). Symptoms could not be better explained by other diseases. 2: 18-80 years old; 3: The patient agrees to participate and signs the informed consent; 4: Can cooperate with regular follow-up and complete the study.
Exclusion criteria
Exclusion criteria: 1: patient with severe heart disease, patients with hepatic and renal insufficiency, patient with malignant tumors; 2: Patients with severe nervous system diseases: cerebral hemorrhage, massive cerebral infarction, subarachnoid hemorrhage, severe encephalitis, epilepsy, craniocerebral trauma, severe mental illness and cognitive dysfunction; 3: Those who have been implanted with metal in the head and have received cochlear implant and cardiac pacemaker installation and can not tolerate AC therapy; 4: Patients with metal foreign bodies, cardiac pacemakers, claustrophobia and other contraindications to MRI examination; 5: Those who have received transcranial magnetic stimulation, transcranial direct current stimulation or other neuromodulation techniques in the past; 6: Patients during pregnancy, lactation and pregnancy preparation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dizziness, depression and anxiety; | — |
Secondary
| Measure | Time frame |
|---|---|
| Balance;anxiety; | — |
Countries
China
Contacts
Public ContactZhao Jiaxin
Shaanxi Provincial People's Hospital
Outcome results
None listed