Temporal lobe epilepsy
Conditions
Interventions
Observation group:None
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Inclusion Criteria for the Mixed Retrospective and Prospective Cohort Study: 1. Fulfills the ILAE (International League Against Epilepsy) diagnostic criteria for temporal lobe epilepsy, with confirmed epileptogenic zone located in the temporal lobe based on ictal symptoms, EEG, cranial MRI, and magnetoencephalography (MEG). 2. Has undergone presurgical evaluation between January 2001 and June 2025. 3. Age between 14 and 65 years inclusive. 4. No gender restrictions. 5. No history of previous intracranial surgery. Inclusion Criteria for the Prospective Cohort Study: 1. Fulfills the ILAE (International League Against Epilepsy) diagnostic criteria for temporal lobe epilepsy, with confirmed epileptogenic zone located in the temporal lobe based on ictal symptoms, EEG, cranial MRI, and MEG. 2. Have undergone surgical evaluation between July 2025 and July 2030. 3. Age between 14 and 65 years inclusive. 4. No gender restrictions. 5. No history of previous intracranial surgery. 6. Informed consent form signed by the patient or their legal representative.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for the Retrospective and Prospective Hybrid Cohort Study: 1.Presence of cardiac pacemakers, metallic implants, or other similar devices; 2.Significant skull abnormalities; 3. Substantial artifacts interference in data acquisition; 4. Incomplete data acquisition; 5. Presence of other severe neurological disorders; 6. According to the judgment of the investigator, any other condition deeming the participant unsuitable for inclusion in this study. Exclusion Criteria for the Prospective Cohort Study: 1. Presence of cardiac pacemakers, metallic implants, or other similar devices; 2. Claustrophobia; 3. Inability to cooperate with MRI examinations; 4.Presence of brain tumors, space-occupying lesions, or other severe neurological disorders; 5. According to the judgment of the investigator, any other condition deeming the participant unsuitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Rating Scale;Hamilton Depression Scale;Montreal Cognitive Assessment ;Pittsburgh Sleep Quality Index;Scalp EEG; | — |
Countries
China
Contacts
Public ContactYicong Lin
Xuanwu Hospital, Capital Medical University
Outcome results
None listed