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Real-world study on the reduction of peri-operative complications in elderly and frail patients with hip fractures by peripheral nerve block anesthesia: a prospective cohort study

Real-world study on the reduction of peri-operative complications in elderly and frail patients with hip fractures by peripheral nerve block anesthesia: a prospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106748
Enrollment
Unknown
Registered
2025-07-29
Start date
2025-08-16
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip fracture

Interventions

Sponsors

Zibo Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
75 Years to No maximum

Inclusion criteria

Inclusion criteria: Age > 75 years old; gender is not restricted; ASA III - IV grade; hip fracture types include intertrochanteric fracture, subtrochanteric fracture, and femoral neck fracture. Elective or emergency open reduction and internal fixation for intertrochanteric fracture, closed reduction and internal fixation for intertrochanteric fracture, femoral head replacement, or total hip replacement.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Multiple traumas, multiple fractures, or other fractures not included in the inclusion criteria, such as pathological fractures, pelvic fractures, femoral fractures; Contraindications to general anesthesia (drug allergy to general anesthesia or any other drugs administered during this study); Contraindications to nerve block (infection at the puncture site, coagulation disorders, international normalized ratio > 1.4, platelet count < 80 × 10^9/L, local anesthetic allergy); Susceptible to malignant hyperthermia.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium;Duration of delirium;Severe postoperative cardiovascular adverse events;Postoperative pain score;Postoperative pulmonary infection;Postoperative AKI;Degree of postoperative frailty;Postoperative cognitive function;

Secondary

MeasureTime frame
Occurrence of intraoperative hypotension;Postoperative PACU stay time;Length of hospital stay;Whether to be admitted to the ICU;Hospitalization expenses;

Countries

China

Contacts

Public ContactQingting Wang

Zibo Central Hospital

653019630@qq.com+86 186 7818 6926

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026