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Clinical study on reducing pulmonary complications after thoracoscopic partial pneumonectomy by conscious prone position ventilation

Clinical study on the effect of postoperative conscious prone position ventilation on early pulmonary complications after thoracoscopic partial pneumonectomy

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106743
Enrollment
Unknown
Registered
2025-07-29
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary complications after thoracoscopic partial pneumonectomy

Interventions

Control group (supine position group, SP group) :Patients in SP group were taken to supine position 72 hours after operation, and received routine lung care and rehabilitation training.
Experimental group (prone position group, PP group):Patients in PP group were given multiple times of awake prone position ventilation according to the actual situation within 72 hours after operation

Sponsors

Shaanxi Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age is 18-80 years old; 2. PS score is 0-1; 3. According to the evaluation of doctors, partial pneumonectomy under endoscope (including wedge resection, segmental resection, single lobectomy, multi-lobectomy, lobectomy combined with wedge resection, sleeve resection, etc.) can be accepted; 4. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Trauma: unstable fractures of cervical vertebra, thoracic vertebra, lumbar vertebra, pelvis and skull; 2. Face: severe trauma and fracture of maxillofacial region; Elevated intraocular pressure or eye surgery = 15 d; 3. Nervous system: high intracranial pressure, brain edema, frequent seizures or mental state changes; 4. Hemorrhage: acute hemorrhagic disease or active bleeding; 5. Hemodynamic instability (heart rate =40 beats /min or =130 beats/min); Suspected myocardial infarction; The mean arterial pressure (map) after the application of vasoactive drugs was = 65 mmhg or = 110 mmhg; 6, airway: airway management difficulties, hemoptysis, tracheotomy = 24 h; 7. Abdomen: middle and late pregnancy, severe abdominal expansion, and abdominal soft tissue injury; 8. Musculoskeletal: kyphosis or late arthritis; 9, body mass index > >40 kg/m2 or weight > >135 kg;; 10. There is an obvious high risk of pulmonary embolism; Treatment of deep venous thrombosis = 2 d; 11. Unable to adjust the position independently or tolerate prone position without the help of others; There is serious pressure injury in the relevant parts; 12. Do not sign the informed consent.

Design outcomes

Primary

MeasureTime frame
Postoperative pulmonary complications;

Secondary

MeasureTime frame
The highest grade of postoperative pulmonary complications;Incidence rate of postoperative adverse events;Oxygenation index in the first 3 days after operation;Length of stay in ICU;Use time of non-invasive ventilation;Time of tracheal intubation again;Unplanned readmission;Total hospitalization time;28-day mortality rate;

Countries

China

Contacts

Public ContactYawei Dou

Shaanxi Provincial People's Hospital

1270189458@qq.com+86 134 6860 1101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026