Effect of Goal-Directed Fluid Therapy Combined with Erector Spinae Plane Block on Perioperative Stress Response and Postoperative Recovery in Patients Undergoing Robot-Assisted Pedicle Screw Fixation

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500106739

Enrollment

Unknown

Registered

2025-07-29

Start date

2025-09-01

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vertebral fracture

Interventions

Test group: Ultrasound-guided Erector Spinae Plane Block (ESPB)

Control group:Conventional general anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 75 years old, ASA classification I to III; 2. Scheduled for elective robot-assisted posterior lumbar pedicle screw fixation surgery; 3. Normal preoperative cognitive function (MoCA score >= 26 points).

Exclusion criteria

Exclusion criteria: 1. Severe cardiac, pulmonary, hepatic, or renal insufficiency (Child-Pugh class C, eGFR 1.5 or PLT <80×10?/L). 3. Infection at the puncture site or spinal deformity. 4. History of allergy to ropivacaine. 5. Long-term use of glucocorticoids or immunosuppressive agents.

Design outcomes

Primary

Measure	Time frame
Cor;NE;GLU;Opioid consumption;	—

Secondary

Measure	Time frame
heart rate, HR;mean arterial pressure, MAP;Visual Analog Scale, VAS;	—

Countries

China

Contacts

Public ContactHu Dandan

Huai'an 82 hospital

jsxyhdd@163.com+86 158 5174 0810

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026