Osteoarthritis of the knee
Conditions
Interventions
Adductor canal block group (Group A):adductor canal block
Dexmedetomidine group (group B):At the beginning of anesthesia induction, dexmedetomidine (4µg/ml) was administered as a loading dose of 0.5µg/kg intraoperatively
At the beginning of anesthesia induct
Adductor canal block combined with dexmedetomidine group (Group C):Adductor tube block combined with low-dose pumping of dexmedetomidine
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age: 65~80 years old; 2.The American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level; 3. Body mass index:18.5~27.9 kg/m^2
Exclusion criteria
Exclusion criteria: 1.Other surgeries on the same knee; 2.Patients who are allergic to the drugs used in this study or opioid abuse; 3.contraindications to nerve block; 4.local skin infection damage; 5.coagulation dysfunction; 6.bradycardia with atrioventricular block; 7.severe liver, kidney, cardiovascular and cerebrovascular and central nervous system diseases; 8.communication disorders; 9.refuse to participate in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour postoperative Quality of Recovery 15-item scale score (QoR-15); | — |
Secondary
| Measure | Time frame |
|---|---|
| 48-hour postoperative Quality of Recovery 15-item scale score (QoR-15);Visual analogue score;Time to first postoperative rescue analgesia;The total amount of rescue analgesic drugs was used 24 hours after surgery;Pittsburgh Sleep Quality Score;Hemodynamics; | — |
Countries
China
Contacts
Public ContactWang Gongming
Shandong Provincial Hospital
Outcome results
None listed