hepatocellular carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult (>=18 years old); 2. The patient underwent liver cancer resection surgery at our hospital; 3. The patient was diagnosed with pure MAFLD HCC and mixed MAFLD and HBV HCC; The diagnostic criteria for MAFLD are: Overweight or obesity: defined as Caucasian BMI>=25kg/m ^ 2 or Asian BMI>=23kg/m ^ 2. Thin/Normal Weight: White BMI=102/88 cm (or Asian males and females>=90/80 cm) Blood pressure>=130/85 mmHg or receiving specific medication treatment Plasma triglycerides>=150 mg/dL (>=1.70 mmol/l) or specific drug therapy Plasma HDL cholesterol: Male=2.5 Plasma high-sensitivity C-reactive protein (hs CRP) level>2 mg/L Having 1 or 3 can be diagnosed as MAFLD. Having at least two metabolic abnormality risk factors can also be diagnosed as MAFLD. 4. Child Pugh classification of liver function: A or B grade; 5. No severe cardiovascular or renal dysfunction; 6. Having detailed preoperative clinical features, prognostic data, and pathological tissue specimens.
Exclusion criteria
Exclusion criteria: 1. Merge with other malignant tumors; 2. Metastatic liver cancer; 3. Tumor recurrence and subsequent resection; 4. Accidental death due to other illnesses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;progression free survival; | — |
Countries
China
Contacts
Zhongshan Hospital, Fudan University