Idiopathic Normal Pressure Hydrocephalus (iNPH)
Conditions
Interventions
Intervention:Cognitive-Motor Dual-Task Rehabilitation
Sponsors
Shanghai Tenth People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Consistent with the 2022 version of the Expert Consensus on the Diagnosis and Treatment of Isopathic Normal Pressure Hydrocephalus in China, diagnosed with possible iNPH and clinically confirmed iNPH 2. Evans ratio of brain images>30% 3. Adults aged 18-80 years 4. The cerebrospinal fluid pressure measurement of lumbar puncture is less than 200mmH2O, and the cerebrospinal fluid biochemistry routine is normal 5. Examination excludes diseases with clear causes of ventricular enlargement and other diseases affecting gait disorders 6. Able to stand for 5min without assistance 7. MMSE>17, able to cooperate with the completion of cognitive and gait assessments 8. Sign the informed consent form
Exclusion criteria
Exclusion criteria: 1. Unstable vital signs, severe heart, lung, kidney, and liver diseases 2. Limb dysfunction that exists before the brain lesion 3. Abnormal postural control caused by other reasons, such as cerebellar disease, vestibular lesions, peripheral nerve and skeletal muscle lesions, etc 4. Severe cognitive impairment, severe depression, aphasia and blindness that cannot cooperate with cognitive gait assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Idiopathic Normal Pressure Hydrocephalus Grading Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postural Control Assessment;Cognitive Function Evaluation; | — |
Countries
China
Contacts
Public ContactLiu Xueyuan
Shanghai Tenth People's Hospital Department of Neurology, Tongji University
Outcome results
None listed