chronic consciousness disorders
Conditions
Interventions
Brain-Computer Interface Visual Motor Imagination Task Group:Non-invasive brain-computer interface based on electroencephalography.
Visual cycling movement imagination task training.
Conventional picture movement imagination task group:Patients undergo cycling exercise imagination task training based on pictures.
Sponsors
The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–70 years; 2. Diagnosed with UWS and MCS based on the CRS-R scale; 3. Disease duration >= 28 days; 4. Causes include ischaemic-hypoxic encephalopathy, traumatic brain injury, stroke, etc.; 5. Right-handed individuals.
Exclusion criteria
Exclusion criteria: 1. Individuals with a history of other neurological or psychiatric disorders prior to coma; 2. Individuals who have undergone cranial bone flap removal or repair surgery, or have implanted neural stimulators; 3. Individuals taking medications that affect cortical excitability; 4. Individuals with uncontrollable epilepsy or involuntary movements; 5. Individuals with severe visual or hearing impairments, unable to complete event-related potential testing or exhibiting ‘brain-computer interface non-response’; 6. Family members refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coma Recovery Scale –Revised (CRS-R);Relative power analysis;functional near-infrared spectroscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| event-related potential;Coherence;Phase Locking Value;Phase Lag Index;weight Phase Lag Index; | — |
Countries
China
Contacts
Public ContactZhenzhen Gao
The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)
Outcome results
None listed