low back pain
Conditions
Interventions
Single group:Intramuscular injection of 5 mL PRP into the thoracolumbar fascia in weeks 1, 2, and 3
Sponsors
The First Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for myofascial low back pain: There is regional pain in the lower back and lumbar area, palpable muscle taut bands are present, and referred pain or sensory changes are localized near a specific trigger point. The tender point within the taut band can be accurately identified. There may be mild muscle weakness or a certain degree of limitation in range of motion; 2. Moderate to severe pain, with a Visual Analog Scale (VAS) score >=4; 3. Patients are aged between 18 and 65 years; 4. Duration of symptoms exceeds 1 month; 5. Patients have a thorough understanding of the study details, and demonstrate good compliance and a high level of cooperation; 6. Informed consent has been obtained.
Exclusion criteria
Exclusion criteria: 1. Low back pain caused by any other reasons, including but not limited to lumbar disc herniation, lumbar spinal stenosis, ankylosing spondylitis, spinal tumors, spinal tuberculosis, spinal cord infections, etc; 2. Patients with severe diabetes or drug allergies; 3. Patients with fever, upper respiratory tract infection, or other infectious diseases; 4. Patients with systemic diseases or organ dysfunction; 5. Patients with coagulation disorders or those taking anticoagulant medications; 6. Patients with infections in the injection site or surrounding soft tissues; 7. Patients currently using corticosteroids or undergoing other treatments that may affect the observed outcomes of this study; 8. Patients with severe mental illnesses who are unable to cooperate; 9. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale,VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| OswestryDisability Index, ODI ;Japanese Orthopaedic Associationscores, JOA;Medical Outcom Study 36-Item Short-Form Health Survey, SF-36; | — |
Countries
China
Contacts
Public ContactGao Bo
The First Affiliated Hospital of Air Force Medical University
Outcome results
None listed