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Efficacy and Safety of Fractional CO2 Laser in the Prevention of Hypertrophic Scar Formation After Cesarean Section In Women Predisposed To Scar Formation: a Prospective Randomized Controlled Study in Chinese Patients

Efficacy and Safety of Fractional CO2 Laser in the Prevention of Hypertrophic Scar Formation After Cesarean Section In Women Predisposed To Scar Formation: a Prospective Randomized Controlled Study in Chinese Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106688
Enrollment
Unknown
Registered
2025-07-28
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of hypertrophic scars formation post-cesarean section surgery

Interventions

Experimental group:Will receive fractional CO2 laser treatment 7 days post cesarean section surgery ,energy 17.5-22.5mj, density 5%
Control group:Will not receive Fractional CO2 laser treatment

Sponsors

Dematology Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Age 22-45 years old; 2. Chinese nationality; 3. Signed informed consent; 4. Women with a history of hypertrophic scarring after the first caesarean section after the second caesarean section; 5. History of hypertrophic scarring; 6. There is no bleeding, ulceration or infection at the incision site after surgery.

Exclusion criteria

Exclusion criteria: 1. Have received anti-scarring treatments, such as steroid injections or topical use; 2. Laser treatment of caesarean section scars; 3. Current cancer or uncontrolled systemic disease.

Design outcomes

Primary

MeasureTime frame
Patient and observer scar assessment scale;

Secondary

MeasureTime frame
Vancouver scar scale(VSS);Antera 3D;Investigator global assessment (IGA);Patient satisfaction;Vsiual Analogue Scale (VAS);Safety indicator;

Countries

China

Contacts

Public ContactZhenfeng Liu

Dermatology Hospital of Southern Medical University (Guangdong Dermatology Hospital)

liuzhenfengpuma@163.com+86 20 83027579

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026