acute exacerbation chronic obstructive pulmonary disease
Conditions
Interventions
Group of AECOPD Stage I Trial:Level I rehabilitation exercise program
Control group of grade I AECOPD:Regular exercise rehabilitation exercises
Experimental group of AECOPD grade II:Level II Sports Rehabilitation Exercises
Control group of AECOPD grade II:Regular exercise rehabilitation exercises
The AECOPD III-level treatment group:Level III Sports Rehabilitation Exercises
Control group of AECOPD grade III:Regular exercise rehabilitation exercises
Sponsors
Second Affiliated Hospital of Zunyi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. According to the diagnostic criteria for COPD in the 2024 edition of GOLD (Global Initiative for Chronic Obstructive Lung Disease), and the condition is in an acute exacerbation phase; 2. Meets any one of the following criteria from the 2022 EXODUS (EXpert consensus On Diaphragm Ultra Sonography in the critically ill) guidelines: diaphragm mobility <2 cm, diaphragm thickness <2.2 mm, or diaphragm thickening fraction <20%; 3 Age between 40 and 80 years; 4.Be conscious, able to communicate verbally without difficulty, and willing to cooperate with the study.
Exclusion criteria
Exclusion criteria: 1.Existence of contraindications for exercise: uncontrolled hypertension (>180/110 mmHg) and hypotension (<90/60 mmHg); severe cardiovascular disease; concomitant acute exacerbation of bronchial asthma, pulmonary embolism, pneumothorax, etc.; presence of conditions affecting neuromuscular diseases, osteoarthritis, etc. 2. Chest deformities, known diaphragmatic paralysis, or chronic neuromuscular diseases; 3. Poor compliance during the study, unwillingness to cooperate with relevant examinations and interventions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Malondialdehyde;Total Antioxidant Capacity;Superoxide Dismutase;diaphragm excursion;diaphragm thickness at end inspiration,DTei;diaphragm thickness at end expiration;diaphragm thickening fraction; | — |
Countries
China
Contacts
Public ContactHongmin Ran
The Second Affiliated Hospital of Zunyi Medical University
Outcome results
None listed