Depressive disorder
Conditions
Interventions
Group1:TMS intervention for sad face:Transcranial magnetic stimulation (TMS) was used to intervene the occipito-facial brain region with a figure 8 coil at a frequency of 10Hz and an intensity of 0.5s
Group2:TMS intervention forneutral face:Transcranial magnetic stimulation (TMS) was used to intervene the occipito-facial brain region with a figure 8 coil at a frequency of 10Hz and an intensity of 0
Group3: The intervention of TMS in control brain area for negative face:Transcranial magnetic stimulation (TMS) was used to intervene the occipito-facial brain region with a figure 8 coil at a frequen
Healthy control group:none
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Meet the DSM-V clinical diagnostic criteria for depression; 2) Age: 18-60 years old, right-handed; Chinese speakers; 3) Obtain the patient's written informed consent; 4) Obtain the patient's written informed consent; 5) Normal vision or normal vision after correction; 6) Hamilton Depression Scale 17 items score > 17 7) Initial diagnosis or stable medication for more than 2 weeks Healthy persons must comply with items 2-5.
Exclusion criteria
Exclusion criteria: 1) Schizoaffective disorder, schizophrenia, mental retardation, generalized developmental disorder, delirium, dementia, memory impairment, or other cognitive impairment meeting the DSM-V diagnostic criteria; Those at high risk of suicide; Have epilepsy or a family history of epilepsy; 2) suffering from serious and unstable physical diseases; 3) Use of rTMS or MECT within 3 months before enrollment; 4) Contraindications for MRI scanning (the MRI safety review form needs to be completed when signing the informed consent form); 5) Difficult to cooperate with the completion of the assessment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fixation duration;Accuracy rate;Reaction time; | — |
Countries
China
Contacts
Public ContactLin Lu
Peking University Sixth Hospital, Beijing, China
Outcome results
None listed