Garlic consumption reduces radiation-induced oral mucositis in nasopharyngeal carcinoma

Garlic consumption reduces the incidence of radiation-induced oral mucositis in nasopharyngeal carcinoma patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500106672

Enrollment

Unknown

Registered

2025-07-28

Start date

2025-08-01

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasopharyngeal Carcinoma

Interventions

Intervention Group:Consumption of garlic on the basis of the control group

Control group:Routine treatment and care

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Pathologically confirmed nasopharyngeal carcinoma (WHO Type II-III) scheduled to receive IMRT (>= 60 Gy); 2.Aged >= 18 years, KPS score >= 80, and intact oral mucosa (WHO Grade 0); 3.Having signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Allergic to allicin or having used other mucosal protective agents within 4 weeks; 2.Active oral infection, autoimmune diseases, or severe hepatic/renal insufficiency; 3.Pregnancy, mental disorders, or a history of previous head and neck radiotherapy; 4.Patients with other oral diseases.

Design outcomes

Primary

Measure	Time frame
Radiation-induced Oral Mucositis;	—

Countries

China

Contacts

Public ContactSu Biling

Fujian Cancer Hospital

798528676@qq.com+86 188 5049 2692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026