sore throat
Conditions
Interventions
Group B:Receiving 2 mg/kg flurbiprofen axetil after surgery
Group A:Receiving 2 mg/kg flurbiprofen axetil before surgery.
Group O:Receiving an equal amount of 0.9% normal saline solution intravenously
Sponsors
China-Japan Union Hospital of Jilin University , Changchun 130033 China
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 and 65 years. 2. Those with an anesthesia risk classification of Grade I - III as evaluated by the American Society of Anesthesiologists (ASA). 3. Those with a laryngoscope exposure classification of Grade I - II. 4. Patients scheduled for elective thyroid resection with intraoperative neuromonitoring (IONM).
Exclusion criteria
Exclusion criteria: 1. Body Mass Index (BMI) >= 30 kg/m² 2. Baseline heart rate < 50 beats per minute 3. Severe cardiovascular and cerebrovascular diseases, liver and kidney diseases 4. Hearing impairment, intellectual disability 5. Long-term use of opioids or sedatives 6. History of coagulation disorders or anticoagulant drug use, risk of cervical spine injury 7. Patients with contraindications to the drugs used in this study 8. History of maxillofacial surgery 9. Chronic respiratory diseases, recent respiratory tract infections, chronic cough, smoking history 10. Tracheal intubation time exceeding 4 hours or failure to extubate within 1 hour after surgery, and patients transferred to the intensive care unit with the tube in place after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Postoperative Airway Complications at 6 Hours.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of postoperative sore throat at 6122472 hours.; | — |
Countries
China
Contacts
Public ContactLongyun Li
China-Japan Union Hospital of Jilin University
Outcome results
None listed