Depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with depression: Aged between 18 and 65 years old; meeting the diagnostic criteria for depressive episode (including first-episode and recurrent depressive disorder patients) in the 10th edition of the International Classification of Diseases (ICD-10); the total score of the Hamilton Depression Rating Scale (HAMD) > 17; being of Han ethnicity; all participants not taking psychiatric or sleep medications for at least 2 weeks; avoiding alcohol and drug use 2 weeks before the start of the study; participants maintaining a regular sleep schedule for at least 5 days before polysomnography (PSG) and completing a sleep diary; fully understanding the polysomnography monitoring method and safety, being willing to actively cooperate with the test, and signing the informed consent form. Healthy control group: age 18-65 years; Healthy people without major physical or mental illness; fully understand the method and safety of cerebral polysomnography, and be willing to actively cooperate with the test and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Suffering from disorders of consciousness, mental retardation, brain trauma, and other mental illnesses; organic psychosis, history of epilepsy and family history of epilepsy; depression caused by other psychoactive substances and non-addictive substances; use of anti-epileptic drugs, such as valproate, carbamazepine, etc.; abnormal thyroid function, nervous system diseases; pregnant women and lactating women; individuals with a strong suicidal intention in the acute phase who need to be immediately referred for clinical intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a- wave power spectral density; | — |
Secondary
| Measure | Time frame |
|---|---|
| ß - wave power spectral density;?- wave power spectral density;d wave power spectral density;?- wave power spectral density; | — |
Countries
China
Contacts
Xianyang Central Hospital